Evaluasi Penggunaan Obat Pada Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisis Di Rsud Toto Kabila Periode 2017-2018
Abstract
Chronic Renal Failure (CRF) is kidney damage with a decrease in Glomerular Filtration Rate (LFG) of less than 60mL/min/1.73 m2 during (at least) 3 months. Hemodialysis therapy is the most widely used CRF therapy. Due to certain conditions, in addition to receiving hemodialysis therapy, patients with CRF also
receive oral drug therapy. This is intended to overcome complications both from CRF and hemodialysis therapy itself. This study aims to evaluate drugs use in patients with CRF with hemodialysis based on four aspects, namely the proper patient, the proper medication, the proper indication and the proper dose according to the standard of therapy. This research was a descriptive study using a cross sectional design with data collection done retrospectively on patients undergoing hemodialysis in Regional General Hospitalof Toto Kabila Hospital January 2017-October 2018. 43 patients were taken as samples by purposive sampling method that met the criteria. The data obtained were analyzed by univariate analysis.The results showed that the use of drugs in kidney failure patients undergoing hemodialysis in Regional General Hospitalof Toto Kabila Hospital in the period of January2017-October 2018 based on the four aspects were as follows: proper patient of 100%; proper drug of 86.05% and improper drug of 13.95%; proper indication of 83.72% and improper indication of 16.28%; proper dosage of 53.49%; and improper dosage of 46.51%.Overall, the drugs use evaluation results show that the drugs use on patients with Chronic Rena Failure undergoing hemodialysis in Regional General Hospitalof Toto Kabila Hospital in the period January 2017-October 2018 can be included in the good category.
Keywords— Chronic Kidney Failure, Hemodialysis, Gorontalo
References
Kemenkes RI, 2017, Situasi Penyakit Ginjal Kronis.
Infodatin. Pusat Data dan Informasi Kementerian
Kesehatan RI : Jakarta.
Corrigan, RM. 2011. The experience of the older adult
with end-stage renal disease on hemodialysis. Queen’s
University: Canada.
Hill NR, Fatoba ST, Oke JL, Hirst JA, O’Callaghan CA,
Lasserson DS. 2016. Global prevalence of chronic
kidney disease - A systematic review and meta-analysis.
PLoS One. 2016 Jul 6;11(7):e0158765. doi:
1371/journal.pone.0158765.
Kenward, R., dan Tan, C.K.2003.Penggunaan Obat
Pada Gangguan Ginjal, dalam Aslam Farmasi Klinis:
Menuju Pengobatan Rasional dan Penghargaan Pilihan
Pasien 2003. PT.Elex Media Komputindo Gramedia :
Jakarta
Brunner & Suddarth. 2002. Textbook of Medical-
Surgical Nursing. Lippincott Williams & Wilkins:
Philadelphia
Corrigan, RM. 2011. The experience of the older adult
with end-stage renal disease on hemodialysis. Queen’s
University: Canada.
Holley, J.F. Berns, J.S. dan Post, T.W. 2007. Acute
complications during Hemodialysis. Hemodialysis.
http://www.uptodate.com. (Diakses tanggal 25
Desember 2018)
Zhang, Qui-Li, dan Rothenbacher, D. 2008.Prevalence
of Chronic Kidney Disease in Population Based Studies:
Systematic Review. BMC Public Health.
PMID:18405348. PMCID:PMC2377260. DOI:10.1186/1471-2458-8-117
Supadmi, W. 2011. Evaluasi Penggunaan Obat Anti
Hipertensi Pada Pasien Gagal Ginjal Kronik Yang
Menjalani Hemodialisis. Pharmaciana, Vol. 1., No.1.:
Yogyakarta. DOI:
http://dx.doi.org/10.12928/pharmaciana.v1i1.517
Kring, D. L. & Crane, P. B. 2009. Factors
affectingquality of life in persons on
hemodialysis.Nephrol Nurs J. Jan-Feb;36(1):15-24, 55.
Kemenkes RI, 2010. Profil Kesehatan Indonesia 2009.
Departemen Kesehatan Republik Indonesia : Jakarta
Weinstein JR, Anderson S. 2010. The aging kidney:
Physiological changes. Adv Chronic Kidney Dis. Jul;
(4): 302–307. doi: 10.1053/j.ackd.2010.05.002
Aisara, S. Azmi, S. Yanni M. 2018. Gambaran Klinis
Penderita Penyakit Ginjal Kronik yang Menjalani
Hemodialisis di RSUP Dr. M. Djamil Padang. Jurnal
Kesehatan Andalas. 2018; 7(1). Pp 42-50
PERNEFRI, 2017. 10 th Report Of Indonesian Renal
Registry. Perkumpulan Nefrologi Indonesia
(PERNEFRI) : Jakarta
Sukandar E. 2013. Nefrologi klinik. Ed 4. Bandung:
Pusat informasi ilmiah bagian ilmu penyakit dalam
fakultas kedokteran UNPAD. hal. 465 – 99.
Chobanian AV, Bakris GL, Black HR, Cushman WC,
Green LA, Izzo JL et al. 2003. JNC 7 Express. The
Seventh report of the joint national comimitte on
prevention, detection, evaluation, and treatment of high
blood pressure. NIH Publication No. 03-5233: Boston
Delima.Tjitra, E. Tana, L. Halim FS.Ghani, L. Siswoyo,
H. Idaiani, S. Andayasari, L. Widowati, L. Gitawati, R.
Sihombing, M. Tjahja, I. Notohartojo. Sintawati.Jovina,
TA. Karyana, M. Nugroho, P. Wibisono, D. Sarwono, J.
Agustin, H. Suhardjono. Sastroasmoro, S. Siswanto.
Faktor Risiko Penyakit Ginjal Kronik : Studi
Kasus Kontrol di Empat Rumah Sakit di Jakarta Tahun
Buletin Penelitian Kesehatan, Vol. 45, No. 1,
Maret 2017: 17 - 26 Jakarta.
Tjokroprawiro, A. 2006. Hidup Sehat dan Bahagia
bersama Diabetes Melitus. Gramedia Pustaka Utama :
Jakarta.
Mubarok, WI. Nurul, C. dan Joko, S. 2015. Standar
Asuhan Keperawatan dan Prosedur Tetap dalam Praktik
Keperawatan Konsep dan Aplikasi dalam Praktik Klinik.
Salemba Medika : Jakarta.
Luntungan, P. Tjitrosantoso, H. Yamlean, P. 2016.
Potensi Drug Related Problems (Drps) Pada Pasien
Gagal Ginjal Di Rawat Inap Rsup Prof. Dr. R. D.
Kandou Manado.UNSRAT. PHARMACONJurnal
Ilmiah Farmasi – UNSRAT Vol. 5 No. 3 AGUSTUS
ISSN 2302 – 2493Manado. Hal 23-33.
Narita, I., Iguchi, S., Omori, K. & Gejyo, F. 2008.
Uremic pruritus in chronic hemodialysis patients.J
Nephrol. 2008 Mar-Apr;21(2):161-5. PMID:18446709
Kobrin, S.M. & Berns, J.S. 2007. Quinine--a tonic too
bitter for hemodialysis-associated muscle
cramps?.Semin Dial. 2007 Sep-Oct;20(5):396-401.
Rahman, M, Griffin, V. 2004. Patternsof
Antihypertensive Medication Use in Hemodialysis
Patients. Am J Health Syst Pharm. 2004 Jul
;61(14):1473-8..
PMID:15332695DOI:10.1093/ajhp/61.14.1473
Departemen Kesehatan, R.I., 2006. Pharmaceutical care
untuk penyakit hipertensi. Jakarta: Direktorat Bina
Farmasi Komunitas Dan Klinik Ditjen Bina Kefarmasian
Dan Alat Kesehatan, hal:73.
Seguchi, C. Shima, T. Misaki, M. Takarada, Y. Okazaki,
T. 1992.Serum erythropoietin concentration and iron
status in patients on chronic hemodialysis. Clin Chem.
Feb;38(2):199-203. PMID:1541000
Tjay, TH dan Rahardja, K. 2007.Obat-Obat Penting
Edisi Keenam Cetakan ke-3.PT Elex Media Komputindo
: Jakarta.
Monica, C. 2017. Kajian Drug Related Problem (Drps)
Pada Pasien Penyakit Ginjal Kronik Stadium V Yang
Menjalani Hemodialisa Di Instalasi Hemodialisa Rsup
Dr. M. DjamilPadang. Universitas Andalas : Padang
Makani H, Bangalore S, Romero J, Wever-Pinzon O,
Messerli FH. 2011. Effect of reninangiotensin system
blockade on calcium channel blocker-associated
peripheral edema. Am J Med. 2011;124(2):128–135.
PMID:21295192. DOI:10.1016/j.amjmed.2010.08.007
Ozkan M1, Oflaz SB, Kocaman N, Ozseker F, Gelincik
A, Büyüköztürk S, Ozkan S, Colakoğlu B. 2007.
Psychiatric morbidity and quality of life in patients with
chronic idiopathic urticaria.Ann Allergy Asthma
Immunol. 2007 Jul;99(1):29-33. PMID:17650826.
DOI:10.1016/S1081-1206(10)60617-5
Tomasello, Sarah., 2008. Secondary
Hyperparathyroidism and Chronic Kidney Disease,
Diabetes Spectrum Volume 21, Number 1.,p. 19-22
Fajriansyah. Hadijah Tahir, Almi Kombong. 2016.
Kajian Drug Relation Problem (Drps) Kategori Interaksi
Obat, Over Dosis Dan Dosis Subterapi Pada Pasien
Gagal Jantung Kongestif Di RSUP Universitas
Hasanuddin. Jurnal Ilmiah Farmasi. Vol.5, No.1.
Februari 2016. ISSN : 2302-2493.
DOI: https://doi.org/10.30591/pjif.v8i2.1470
Refbacks
- There are currently no refbacks.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Â
===============================================================
Parapemikir : Jurnal Ilmiah Farmasi
Program Studi D-3 Farmasi
Politeknik Harapan Bersama Tegal
Jl. Mataram No.09 Pesurungan Lor Kota Tegal
Telp. +62283 - 352000
Email :[email protected]
Â
Copyright: Parapemikir : Jurnal Ilmiah Farmasi p-ISSN:2089-5313 e-ISSN:2549-5062
Â
===============================================================
Â
Parapemikir Indexed By :Â
![]() | ![]() | ![]() | ![]() |
![]() | ![]() | ![]() | Â |
Â

This work is licensed under a Creative Commons Attribution 4.0 International License.










