Evaluasi Penggunaan Antibiotik Dengan Metode Gyssens Pasien Demam Tifoid Rawat Inap di RSUD Dr. Soedono Madiun Tahun 2019-2020

Satwika Budi Sawitri, Nadia Iha Fatihah, Annis Istiqomah, Rolando Rahardjoputro

Abstract


Typhoid fever is an acute infection of the digestive tract caused by Salmonella typhi bacteria. The main therapy for typhoid fever is the administration of antibiotics. The high incidence of typhoid fever in Indonesia has led to increased antibiotic use and triggered antibiotic resistance. Antibiotic resistance will cause various problems such as incurability of the disease, suprainfection, increased risk of side effects, mortality, morbidity and health costs. This study aims to determine the pattern of antibiotic use and evaluate the rationality of antibiotic use in typhoid fever patients at RSUD Dr. Soedono Madiun qualitatively using the Gyssens method. This study uses a qualitative descriptive method by collecting patient medical records retrospectively with a purposive sampling method. The obtained medical records will be analyzed qualitatively using Gyssens criteria. The results of the qualitative analysis show that from 57 medical records there are 14 types of antibiotics used with thiamphenicol as the most common antibiotic (22%). The results of the qualitative analysis are antibiotic prescriptions for typhoid fever at Dr. Soedono Madiun Regional General Hospital. Soedono Madiun is in accordance with 72% accuracy, namely category IV A as many as 9 (15%), category IV B as many as 2 (4%), category IV D as many as 5 (9%), category III B as many as 9 (15%), category II A as many as 1 (2%), category II B as many as 4 (7%), category I as many as 1 (2%) and category 0 as many as 26 (46%).

Keywords


Antibiotic; Typhoid Fever; Gyssens Method

References


G. Puspitasari, K. S. Artani and T. S. Wardani, "Efektivitas Antibiotik Pasien Demam Tifoid Rawat Inap di RSAU dr. Siswanto Lanud Adi Sumarmo Tahun 2022," Parapemikir : Jurnal Ilmiah Farmasi, vol. 12, no. 3, pp. 328-338, 2023.

Masriadi, Epidemiologi Penyakit Menular, Depok: Rajawali Pers, 2017.

P. Indriyani, N. R. A. Harahap and W. N. Hasmar, "Evaluasi Penggunaan Antibiotik Pada Pasien Demam Tifoid di Rumah Sakit "X" Swasta Bekasi Pada Tahun 2020," Jurnal Mitra Kesehatan (JMK), vol. 4, no. 2, pp. 108-113, 2022.

Direktorat Jendral PP & PL, Keputusan Menteri Kesehatan Republik Indonesia Nomor 364 Tentang Pedoman Pengendalian Demam Tifoid, Jakarta: Depkes RI, 2007.

T. D. Anggraini, "Tinjauan Pola Penggunaan Antibiotik Pada Pasien Anak Demam Tifoid di Instalasi Rawat Inap RSUP dr. Kariadi Semarang Tahun 2009," Jurnal Farmasi (Journal of Pharmacy), vol. 2, no. 1, pp. 54-62, 2013.

R. S. Kelanit, D. Y. P. Runtuboi and T. Gunaedi, "Uji Resistensi Antibiotik dan Deteksi Gen Plasmid IncHI1 Salmonella typhi Isolat Jayapura," Jurnal Biologi Papua, vol. 8, no. 1, p. 48–56, 2016.

S. Megawati, F. Carolina and Nuraini, "Evaluasi Penggunaan Antibiotik Dengan Metode Gyssens Pada Pasien Demam Tifoid Anak di Instalasi Rawat Inap RSUP Dr. Sitanala Tahun 2019-2021," Jurnal Insan Farmasi Indonesia, vol. 6, no. 3, pp. 127-138, 2023.

T. Ramadhan, "Meninjau Kembali Algoritma Gyssens : Sebuah Narrative Review," Bencoolen Journal of Pharmacy, vol. 4, no. 1, pp. 25-40, 2024.

I. Yuniar, M. R. Karyanti, T. Tambunan and N. A. Rizkyani, "Evaluasi Penggunaan Antibiotik dengan Kartu Monitoring Antibiotik Gyssens," Sari Pediatri, vol. 14, no. 6, pp. 384-390, 2013.

Surahman, Metodologi Penelitian, Jakarta: Kementerian Kesehatan Republik Indonesia, 2016.

R. W. Sundariningrum, D. B. Setyanto and R. I. Natadidjaja, "Evaluasi Kualitatif Antibiotik Metode Gyssens dengan Konsep Regulasi Antimikroba Sistem Prospektif RASPRO pada Pneumonia di Ruang Rawat Intensif Anak," Sari Pediatri, vol. 22, no. 2, pp. 109-114, 2020.

S. A. Putri and D. M. Oktavilantika, "Evaluation of the Rationality of Antibiotic Use in Thypoid Fever Patients in Inpatient Installation of Hospitalization “X” Indramayu With Gyssens Method," Jurnal Farmasi dan Farmakoinformatika, vol. 1, no. 1, pp. 1-13, 2023.

P. B. S. Kinanta, D. G. D. D. Santhi and A. A. Ngurah, "Profil Pemberian Antibiotik dan Perbaikan Klinis Demam Pada Pasien Anak Dengan Demam Tifoid di RSUP Sanglah Denpasar," Jurnal Medika Udayana, vol. 9, no. 3, pp. 10-14, 2020.

Anonim, "Pedoman Penggunaan Antibiotik," Kementerian Kesehatan Republik Indonesia, Jakarta, 2021.

W. Lekok, R. I. Natadidjaja and A. Dharmayanti, "Regulasi Antimikroba Sistem Prospektif (RASPRO): Sistem Tata Guna Antibiotik Untuk Kendali Mutu dan Kendali Biaya di Rumah Sakit Sebagai Upaya Menurunkan Beban BPJS Kesehatan," Media Bisnis, vol. 12, no. 1, pp. 83-88, 2020.

F. Umar, Pedoman Pelayanan Kefarmasian Untuk Terapi Antibiotik, Jakarta: Kementerian Kesehatan Republik Indonesia, 2011.

S. Indrawaty, Modul Penggunaan Obat Rasional, Jakarta: Kementerian Kesehatan Republik Indonesia, 2011.

W. M. Sari, T. A. Listyani and I. N. Khasanah, "Analisis Rasionalitas Penggunaan Antibiotik Pada Pasien Infeksi Saluran Pernafasan Akut (ISPA) Rawat Jalan di RSUD Dr. Moewardi Surakarta," Parapemikir : Jurnal Ilmiah Farmasi, vol. 12, no. 3, pp. 439-445, 2023.




DOI: https://doi.org/10.30591/pjif.v14i3.9642

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